Zantac (Ranitidine) Alternatives - Famotidine, Nexium, Omeprazole

hello everybody welcome back this is

quake ooh I'm a pharmacist today I'm

gonna be doing a short video as a flow

up to the one I did on the zantac or an

ET beam I'm gonna be looking at some

alternatives that you can consider if

you are one of those that take zantac or

a knitted in and you've recently heard

about the FDA discovering that possible

human carcinogens may be containing some

of these product if this is news to you

then I suggest that you check out my

video I'm gonna put a card right out

there and also I'll put a link at the

end of this video so you can just click

on it and watch that particular video

also as a little disclaimer I want to

mention that this video is for

informational purposes only and do not

take any action based on this video

without consulting with your physician

or your local pharmacist first so the

options or alternatives fall into three

main groups we have the antacids we have

the h2 receptor blockers and we have the

proton pump inhibitors typically we call

them PP eyes so starting with the

antacids this work by direct

neutralization of acid in the stomach as

you already aware the stomach produces a

lot of acid hydrochloric acid to be

precise and this is what for the most

part is guilty in acid reflux so what

these antacids do is they go there and

just like we remember from your high

school chemistry it's just a

neutralization reaction it just

neutralizes the acids and once you have

the acid neutralized the discomfort is

relieved the good thing about antacids

is that they are quite fast-acting they

go in there instructing right away and

the disadvantage though is that they

actually don't last as long so it is

generally not the first choice for

somebody that has a repetitive heartburn

that is if your heartburn occurs

frequently you're probably better off on

something else and not the regular

antacids typical examples in this group

include Maalox mylanta and tums for the

most part these preparations contain

some combination of aluminum hydroxide

or magnesium hydroxide the reasoning is


aluminium salts tend to cause


while magnesium salts tend to cause


the hope is that they will balance out

each other some preparations also

contain simethicone which is to relieve

gas caution should however be exercised

in elderly patients or patients with

kidney disease

tuturro due to the risk of developing

magnesium or aluminium toxicity as these

levels can quickly build up also people

with ulcerative colitis can have the

situation aggravated by the laxative

effect of magnesium so such people

should also be cautious in the use of

such antacids Thoms is another antacid

and it's quite effective it is primarily

made of calcium carbonate which can be

constipating or may cause flatulence but

on the whole is generally effective at

neutralizing acid the next class we are

going to consider is the h2 receptor

blockers these are basically and

histamines and they inhibit the binding

of histamine which a chemical in your

body to h2 receptors which ultimately

results in less acid production in your

system I know you're probably wondering

how this relates to the other end

histamines that we take for seasonal

allergies etc well this one binds to the

HT receptors while the other ones for

seasonal allergies like claritin and

zyrtec they bind primarily to the h1

receptors and binding to each of these

receptors which of these two different

receptors actually causes different from

a collage achill reactions it is when

looking at this point that zantac or

ranitidine actually belongs to this

class other members of this class

include famotidine which is marketed as

pepcid and then we have cimetidine which

is marketed as tagamet they are

available either as over-the-counter

items or as prescriptions so depending

on what you're using it for what the

need is you may either be taking a

prescription or you may just be grabbing

the over-the-counter version for for

primarily heartburn famotidine or pepcid

generally causes very infrequent adverse

effects sometimes people may experience

a headache in about four point seven

percent of the people dizziness

constipation and diarrhea all in the low


point something percentages cimetidine

on the other hand has been known to

cause confusion especially in the

elderly and in severely ill patients

this confusion is typically reversible

upon discontinuation of the medication

but that is something that is definitely

worth taking a note of Simon seeding is

also known to cause gynecomastia which

is swelling or enlargement of the male

breast tissue and this occurs in about

4% of the population so that is

something definitely worth noting it is

also not typically recommended in

patients younger than 16 years of age

unless there the potential benefit

father who is their risk

so in summary h2 receptor blockers

generally are better at taking care of

Khasan reflux due to its ability to

control the acid for longer periods of

time the other thing is that they are

not as fast acting as the antacid so if

you had a meal a spicy meal and you are

in pain right there because of acid

reflux that would not be your first

choice probably an antacid would be

ideal in that circumstance but if you

are somebody that has repeated or

reoccurring heartburn then maybe you

will consider the HT receptor blockers

over there antacids the next set we're

going to take a look at is the proton

pump inhibitors or PPIs as they are

commonly known so PPI is whacked by

inhibiting what is known as proton pumps

which are located in the stomach walls

their responsibility is a secretion of

gastric acid so blocking those pumps

leads to a reduction in the secretion of

acid and therefore relief of heartburn

symptoms members of this class include

esomeprazole or nexium Lancer per zone

or privacy omeprazole prilosec pent-up

resolved or protonix and a few others

these tend to be very effective at

reducing acid production however they

are typically not recommended to be used

for the long term

unless of course long-term use is

recommended by your doctor they

generally do not have the quickest onset

of action so if you are in pain right

now that would not be a first choice

like I discussed with the h2 receptor


and the antacid this one actually take a

little longer to kick in peepee ice are

generally well tolerated by the

occasional headache diarrhea

constipation flatulence sometimes even

nausea cannot be ruled out it is worth

noting that PPI is of course an increase

in their risk for osteoporosis related

fractures usually of the hips the wrist

and the spine the risk is higher in

people that take higher doses and also

for people that take it for a long term

usually over one year long-term use also

increases their risk of malabsorption of

vitamin b12 so people who generally take

PBS for long term tend to be deficient

in vitamin b12 there is also an

increased risk of developing Clostridium

difficile or CF infection of the colon

generally speaking the PP eyes are very

well tolerated and they seem to do the

trick in most cases what I do normally

see though that is PP eyes are typically

given for other conditions like

AUSA's than just regular heartburn but

it is definitely another option that you

can discuss with your doctor so there

you have it folks those are the three

main groups a very high level

description of these groups obviously if

you want me to drill down on one

particular one give me a comment in the

comment section and I'll be glad to look

at that specific one for you once again

thank you so much and stay tuned for

more videos